Welcome to the Australian Calciphylaxis Registry

Thank you for visiting the newly established Australian Calciphylaxis Registry website. Together with the German Calciphylaxis Registry (www.calciphylaxie.de), which is expanding to include other European countries, we see this as the start of international calciphylaxis registry collaboration.

In Germany, data on patients with calciphylaxis (calcific uraemic arteriolopathy) has been collected since 2006 via a similar online registry.

For rare conditions like calciphylaxis, international research networks offer a great opportunity for better understandings of pathophysiology and for advancing clinical management. Thank you for participating in this mission. Please look over the site and if you have or any questions, comments or suggestions for improvements, please do not hesitate to contact us via the website.

what is Calciphylaxis?

Calciphylaxis is a rare, potentially life-threatening syndrome characterized by progressive and painful skin ulcerations associated with medial calcification of medium-sized and small cutaneous arterial vessels. Calciphylaxis primarily affects patients on dialysis or after renal transplantation; however, exceptions have been reported in patients with normal renal function and in association with chronic-inflammatory disease, malignancy or primary hyperparathyroidism. Clinically, calciphylaxis is associated with a high mortality of up to 80%. Superinfection of necrotic skin lesions with subsequent sepsis significantly contributes to this outcome. Many patients also suffer from cardiovascular disease characterized by calcification of larger arterial vessels.

Useful links

  • German Calciphylaxis Registry
    The German Calciphylaxis Registry,
    It is our goal, together with our international research partners, to establish a network for clinical and scientific exchange in the field of calciphylaxis. In Germany, we have been collecting data on patients with calciphylaxis (calcific uraemic arteriolopathy) since 2006 via our online registry.
  • Dialysis Outcomes and Practice Patters
    Dialysis Outcomes and Practice Patters Study program site
    The DOPPS Program collects observational longitudinal data from around the world
    to identify clinical practices with the most benefit for patients.